4nc3: Difference between revisions
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{{STRUCTURE_4nc3| PDB=4nc3 | SCENE= }} | |||
===Crystal structure of the 5-HT2B receptor solved using serial femtosecond crystallography in lipidic cubic phase.=== | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/5HT2B_HUMAN 5HT2B_HUMAN]] This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Plays a role in the regulation of impulsive behavior. | |||
==About this Structure== | |||
[[4nc3]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NC3 OCA]. | |||
[[Category: Barty, A.]] | |||
[[Category: Basu, S.]] | |||
[[Category: Beyerlein, K R.]] | |||
[[Category: Boutet, S.]] | |||
[[Category: Caffrey, M.]] | |||
[[Category: Chapman, H N.]] | |||
[[Category: Cherezov, V.]] | |||
[[Category: Fromme, P.]] | |||
[[Category: Fromme, R.]] | |||
[[Category: GPCR, GPCR Network.]] | |||
[[Category: Gati, C.]] | |||
[[Category: Grotjohann, I.]] | |||
[[Category: Han, G W.]] | |||
[[Category: James, D.]] | |||
[[Category: Katritch, V.]] | |||
[[Category: Kirian, R A.]] | |||
[[Category: Koglin, J E.]] | |||
[[Category: Kupitz, C.]] | |||
[[Category: Li, D.]] | |||
[[Category: Liu, W.]] | |||
[[Category: Messerschmidt, M.]] | |||
[[Category: Nelson, G.]] | |||
[[Category: Rendek, K N.]] | |||
[[Category: Seibert, M M.]] | |||
[[Category: Shah, S T.A.]] | |||
[[Category: Spence, J C.H.]] | |||
[[Category: Stevens, R C.]] | |||
[[Category: Wacker, D.]] | |||
[[Category: Wang, C.]] | |||
[[Category: Wang, D.]] | |||
[[Category: Weierstall, U.]] | |||
[[Category: White, T A.]] | |||
[[Category: Williams, G J.]] | |||
[[Category: Zatsepin, N A.]] | |||
[[Category: Electron transport]] | |||
[[Category: Ergotamine]] | |||
[[Category: Free electron laser]] | |||
[[Category: Gpcr]] | |||
[[Category: Gpcr network]] | |||
[[Category: Human 5ht2b receptor]] | |||
[[Category: Lipidic cubic phase]] | |||
[[Category: Membrane]] | |||
[[Category: Membrane protein]] | |||
[[Category: Novel protein engineering]] | |||
[[Category: Psi-biology]] | |||
[[Category: Serial femtosecond crystallography]] | |||
[[Category: Signaling protein]] | |||
[[Category: Structural genomic]] | |||
Revision as of 10:42, 18 December 2013
Crystal structure of the 5-HT2B receptor solved using serial femtosecond crystallography in lipidic cubic phase.
Function
[5HT2B_HUMAN] This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Plays a role in the regulation of impulsive behavior.
About this Structure
4nc3 is a 1 chain structure. Full crystallographic information is available from OCA.
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Barty, A.
- Basu, S.
- Beyerlein, K R.
- Boutet, S.
- Caffrey, M.
- Chapman, H N.
- Cherezov, V.
- Fromme, P.
- Fromme, R.
- GPCR, GPCR Network.
- Gati, C.
- Grotjohann, I.
- Han, G W.
- James, D.
- Katritch, V.
- Kirian, R A.
- Koglin, J E.
- Kupitz, C.
- Li, D.
- Liu, W.
- Messerschmidt, M.
- Nelson, G.
- Rendek, K N.
- Seibert, M M.
- Shah, S T.A.
- Spence, J C.H.
- Stevens, R C.
- Wacker, D.
- Wang, C.
- Wang, D.
- Weierstall, U.
- White, T A.
- Williams, G J.
- Zatsepin, N A.
- Electron transport
- Ergotamine
- Free electron laser
- Gpcr
- Gpcr network
- Human 5ht2b receptor
- Lipidic cubic phase
- Membrane
- Membrane protein
- Novel protein engineering
- Psi-biology
- Serial femtosecond crystallography
- Signaling protein
- Structural genomic