Single stranded binding protein: Difference between revisions
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Active ''E. coli'' SSB is made of a homotetramer with extensive DNA binding domains that bind to <scene name='56/566528/Dna/1'>a single strand of DNA</scene><ref>PMID:2087220</ref>. The tetramers consist of <scene name='56/566528/E_coli_ssb_alpha_helices/1'>α-helices</scene>, <scene name='56/566528/Beta_sheets/2'>β-sheets</scene>, and random coils. Each subunit contains an α-helix and several β-sheets. The secondary structure also includes a NH2 terminus, which consists of multiple basic residues, or <scene name='56/566528/Basic_residues/2'>positively charged amino acids</scene>. The DNA-binding domain lies within 115 amino acid residues from this terminus. The COOH terminus includes many negatively charged, or <scene name='56/566528/Acidic_residues/5'>acidic amino acids</scene> <ref>PMID:2087220</ref>. | Active ''E. coli'' SSB is made of a homotetramer with extensive DNA binding domains that bind to <scene name='56/566528/Dna/1'>a single strand of DNA</scene><ref>PMID:2087220</ref>. The tetramers consist of <scene name='56/566528/E_coli_ssb_alpha_helices/1'>α-helices</scene>, <scene name='56/566528/Beta_sheets/2'>β-sheets</scene>, and random coils. Each subunit contains an α-helix and several β-sheets. The secondary structure also includes a NH2 terminus, which consists of multiple basic residues, or <scene name='56/566528/Basic_residues/2'>positively charged amino acids</scene>. The DNA-binding domain lies within 115 amino acid residues from this terminus. The COOH terminus includes many negatively charged, or <scene name='56/566528/Acidic_residues/5'>acidic amino acids</scene> <ref>PMID:2087220</ref>. | ||
==Binding Interactions in the Active Site== | ==Binding Interactions in the Active Site== | ||
