2qd1: Difference between revisions

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[[Image:2qd1.gif|left|200px]]<br /><applet load="2qd1" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2qd1.gif|left|200px]]
caption="2qd1, resolution 2.20&Aring;" />
 
'''2.2 Angstrom Structure of the human ferrochelatase variant E343K with substrate bound'''<br />
{{Structure
|PDB= 2qd1 |SIZE=350|CAPTION= <scene name='initialview01'>2qd1</scene>, resolution 2.20&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=PP9:PROTOPORPHYRIN+IX'>PP9</scene>, <scene name='pdbligand=CHD:CHOLIC+ACID'>CHD</scene> and <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Ferrochelatase Ferrochelatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.99.1.1 4.99.1.1]
|GENE= FECH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''2.2 Angstrom Structure of the human ferrochelatase variant E343K with substrate bound'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2QD1 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=FES:'>FES</scene>, <scene name='pdbligand=PP9:'>PP9</scene>, <scene name='pdbligand=CHD:'>CHD</scene> and <scene name='pdbligand=IMD:'>IMD</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Ferrochelatase Ferrochelatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.99.1.1 4.99.1.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QD1 OCA].  
2QD1 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QD1 OCA].  


==Reference==
==Reference==
A pi-helix switch selective for porphyrin deprotonation and product release in human ferrochelatase., Medlock AE, Dailey TA, Ross TA, Dailey HA, Lanzilotta WN, J Mol Biol. 2007 Nov 2;373(4):1006-16. Epub 2007 Aug 23. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17884090 17884090]
A pi-helix switch selective for porphyrin deprotonation and product release in human ferrochelatase., Medlock AE, Dailey TA, Ross TA, Dailey HA, Lanzilotta WN, J Mol Biol. 2007 Nov 2;373(4):1006-16. Epub 2007 Aug 23. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17884090 17884090]
[[Category: Ferrochelatase]]
[[Category: Ferrochelatase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: protopophyrin ix]]
[[Category: protopophyrin ix]]


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