Sandbox Reserved 774: Difference between revisions
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=Structure= | =Structure= | ||
Has a chain structure with 2.4 A resolution, and 2.9 A resolution with a co-factor (acetyl-CoA). The method used to determine the structure was X-ray crystallography. | Has a chain structure with 2.4 A resolution, and 2.9 A resolution with a co-factor (acetyl-CoA). The method used to determine the structure was X-ray crystallography. Sedimentation and crystal structure analysis clearly shows that Hpa2 is dimeric in solution and tetramerizes in the unit crystal. The average B-factor value is 23.9 (main chain) with a 25.4 side chain. The R-factor is 0.19. | ||
=Secondary Structure= | =Secondary Structure= | ||
Most of the secondary structure elements of the monomer contribute residues in dimer contacts. They form a barrel-like with ten strands in which the component strands of the barrel are locked together. | Most of the secondary structure elements of the monomer contribute residues in dimer contacts. They form a barrel-like with ten strands in which the component strands of the barrel are locked together. There are eight beta-strands, four alpha-helices, and ten turns. | ||
==Description== | ==Description== | ||