4cce: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

===STRUCTURE OF MOUSE GALACTOCEREBROSIDASE WITH GALACTOSE: ENZYME- PRODUCT COMPLEX===

~~The entry 4cce is ON HOLD until Paper Publication~~

==Disease==

[[http://www.uniprot.org/uniprot/GALC_MOUSE GALC_MOUSE]] Defects in Galc are the cause of the 'twitcher' phenotype; an autosomal recessive leukodystrophy similar to the human disease (Krabbe disease). This deficiency results in the insufficient catabolism of several galactolipids that are important in the production of normal myelin.

~~Authors~~: ~~Hill, C~~.H., ~~Graham, S.C.~~, ~~Read~~, ~~R.J~~., ~~Deane~~, ~~J.E~~.

==Function==

[[http://www.uniprot.org/uniprot/GALC_MOUSE GALC_MOUSE]] Hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Enzyme with very low activity responsible for the lysosomal catabolism of galactosylceramide, a major lipid in myelin, kidney and epithelial cells of small intestine and colon.<ref>PMID:8769874</ref>

~~Description~~: ~~STRUCTURE OF MOUSE GALACTOCEREBROSIDASE WITH GALACTOSE~~: ~~ENZYME~~-~~PRODUCT COMPLEX~~

==About this Structure==

[[4cce]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CCE OCA].

==Reference==

[[Category: Galactosylceramidase]]

[[Category: Deane, J E.]]

[[Category: Graham, S C.]]

[[Category: Hill, C H.]]

[[Category: Read, R J.]]

[[Category: Enzyme-product complex]]

[[Category: Glycosyl hydrolase]]

[[Category: Hydrolase]]

[[Category: Krabbe disease]]

[[Category: Lysosomal storage disease]]

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+{{STRUCTURE_4cce|  PDB=4cce  |  SCENE=  }}
+===STRUCTURE OF MOUSE GALACTOCEREBROSIDASE WITH GALACTOSE: ENZYME- PRODUCT COMPLEX===
+{{ABSTRACT_PUBMED_24297913}}
-The entry 4cce is ON HOLD  until Paper Publication
+==Disease==
+[[http://www.uniprot.org/uniprot/GALC_MOUSE GALC_MOUSE]] Defects in Galc are the cause of the 'twitcher' phenotype; an autosomal recessive leukodystrophy similar to the human disease (Krabbe disease). This deficiency results in the insufficient catabolism of several galactolipids that are important in the production of normal myelin.
-Authors: Hill, C.H., Graham, S.C., Read, R.J., Deane, J.E.
+==Function==
+[[http://www.uniprot.org/uniprot/GALC_MOUSE GALC_MOUSE]] Hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Enzyme with very low activity responsible for the lysosomal catabolism of galactosylceramide, a major lipid in myelin, kidney and epithelial cells of small intestine and colon.<ref>PMID:8769874</ref>
-Description: STRUCTURE OF MOUSE GALACTOCEREBROSIDASE WITH GALACTOSE: ENZYME-PRODUCT COMPLEX
+==About this Structure==
+[[4cce]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CCE OCA].
+==Reference==
+<ref group="xtra">PMID:024297913</ref><references group="xtra"/><references/>
+[[Category: Galactosylceramidase]]
+[[Category: Deane, J E.]]
+[[Category: Graham, S C.]]
+[[Category: Hill, C H.]]
+[[Category: Read, R J.]]
+[[Category: Enzyme-product complex]]
+[[Category: Glycosyl hydrolase]]
+[[Category: Hydrolase]]
+[[Category: Krabbe disease]]
+[[Category: Lysosomal storage disease]]