2qlb: Difference between revisions

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[[Image:2qlb.jpg|left|200px]]<br /><applet load="2qlb" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2qlb.jpg|left|200px]]
caption="2qlb, resolution 2.25&Aring;" />
 
'''Crystal Structure of caspase-7 with inhibitor AC-ESMD-CHO'''<br />
{{Structure
|PDB= 2qlb |SIZE=350|CAPTION= <scene name='initialview01'>2qlb</scene>, resolution 2.25&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene> and <scene name='pdbligand=CIT:CITRIC ACID'>CIT</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Hydrolase Hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22 3.4.22]
|GENE= CASP7, MCH3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Crystal Structure of caspase-7 with inhibitor AC-ESMD-CHO'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2QLB is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=ACE:'>ACE</scene> and <scene name='pdbligand=CIT:'>CIT</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Hydrolase Hydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22 3.4.22] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QLB OCA].  
2QLB is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QLB OCA].  


==Reference==
==Reference==
Plasticity of S2-S4 specificity pockets of executioner caspase-7 revealed by structural and kinetic analysis., Agniswamy J, Fang B, Weber IT, FEBS J. 2007 Sep;274(18):4752-65. Epub 2007 Aug 14. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17697120 17697120]
Plasticity of S2-S4 specificity pockets of executioner caspase-7 revealed by structural and kinetic analysis., Agniswamy J, Fang B, Weber IT, FEBS J. 2007 Sep;274(18):4752-65. Epub 2007 Aug 14. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17697120 17697120]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
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[[Category: zymogen]]
[[Category: zymogen]]


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