4mz3: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4mz3|  PDB=4mz3  |  SCENE=  }}
===Crystal structure of the voltage-gated sodium channel beta 4 subunit extracellular domain, C131W mutant===


The entry 4mz3 is ON HOLD  until Paper Publication
==Disease==
[[http://www.uniprot.org/uniprot/SCN4B_HUMAN SCN4B_HUMAN]] Romano-Ward syndrome. The disease is caused by mutations affecting the gene represented in this entry.


Authors: Das, S., Van Petegem, F.
==Function==
[[http://www.uniprot.org/uniprot/SCN4B_HUMAN SCN4B_HUMAN]] Modulates channel gating kinetics. Causes negative shifts in the voltage dependence of activation of certain alpha sodium channels, but does not affect the voltage dependence of inactivation (By similarity).  


Description: Crystal Structure of a mutant Ion Channel Domain
==About this Structure==
[[4mz3]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MZ3 OCA].
[[Category: Das, S.]]
[[Category: Petegem, F Van.]]
[[Category: Extracellular]]
[[Category: Ion conductance]]
[[Category: Membrane protein]]