4nod: Difference between revisions

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~~'''Unreleased structure'''~~

===Distinct structural features of TFAM drive mitochondrial DNA packaging versus transcriptional activation===

~~The entry 4nod is ON HOLD~~

==Function==

[[http://www.uniprot.org/uniprot/TFAM_HUMAN TFAM_HUMAN]] Binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation. Required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase. Promotes transcription initiation from the HSP1 and the light strand promoter by binding immediately upstream of transcriptional start sites. Is able to unwind DNA. Bends the mitochondrial light strand promoter DNA into a U-turn shape via its HMG boxes. Required for maintenance of normal levels of mitochondrial DNA. May play a role in organizing and compacting mitochondrial DNA.<ref>PMID:1737790</ref> <ref>PMID:20410300</ref> <ref>PMID:19304746</ref> <ref>PMID:22037172</ref> <ref>PMID:22037171</ref>

~~Authors~~: ~~Ngo, H.B., Lovely, G.A~~.~~, Phillips, R~~.~~, Chan, D~~.C.

==About this Structure==

[[4nod]] is a 12 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NOD OCA].

~~Description~~: ~~Distinct structural features of TFAM drive mitochondrial DNA packaging versus transcriptional activation~~

==Reference==

[[Category: Chan, D C.]]

[[Category: Lovely, G A.]]

[[Category: Ngo, H B.]]

[[Category: Phillips, R.]]

[[Category: Bru substitution to hsp1]]

[[Category: Dna bending]]

[[Category: Hmg]]

[[Category: Mtrnap]]

[[Category: T19]]

[[Category: Tfb2m]]

[[Category: Transcription regulator-dna complex]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+{{STRUCTURE_4nod|  PDB=4nod  |  SCENE=  }}
+===Distinct structural features of TFAM drive mitochondrial DNA packaging versus transcriptional activation===
-The entry 4nod is ON HOLD
+==Function==
+[[http://www.uniprot.org/uniprot/TFAM_HUMAN TFAM_HUMAN]] Binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation. Required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase. Promotes transcription initiation from the HSP1 and the light strand promoter by binding immediately upstream of transcriptional start sites. Is able to unwind DNA. Bends the mitochondrial light strand promoter DNA into a U-turn shape via its HMG boxes. Required for maintenance of normal levels of mitochondrial DNA. May play a role in organizing and compacting mitochondrial DNA.<ref>PMID:1737790</ref> <ref>PMID:20410300</ref> <ref>PMID:19304746</ref> <ref>PMID:22037172</ref> <ref>PMID:22037171</ref>
-Authors: Ngo, H.B., Lovely, G.A., Phillips, R., Chan, D.C.
+==About this Structure==
+[[4nod]] is a 12 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NOD OCA].
-Description: Distinct structural features of TFAM drive mitochondrial DNA packaging versus transcriptional activation
+==Reference==
+<references group="xtra"/><references/>
+[[Category: Chan, D C.]]
+[[Category: Lovely, G A.]]
+[[Category: Ngo, H B.]]
+[[Category: Phillips, R.]]
+[[Category: Bru substitution to hsp1]]
+[[Category: Dna bending]]
+[[Category: Hmg]]
+[[Category: Mtrnap]]
+[[Category: T19]]
+[[Category: Tfb2m]]
+[[Category: Transcription regulator-dna complex]]