4bs5: Difference between revisions
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==About this Structure== | ==About this Structure== | ||
[[4bs5]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BS5 OCA]. | [[4bs5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BS5 OCA]. | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:024224654</ref><references group="xtra"/><references/> | <ref group="xtra">PMID:024224654</ref><references group="xtra"/><references/> | ||
[[Category: Cathepsin S]] | [[Category: Cathepsin S]] | ||
[[Category: Lk3 transgenic mice]] | |||
[[Category: Banner, D W.]] | [[Category: Banner, D W.]] | ||
[[Category: Benz, J.]] | [[Category: Benz, J.]] | ||
Revision as of 07:04, 15 January 2014
MOUSE CATHEPSIN S WITH COVALENT LIGAND
Template:ABSTRACT PUBMED 24224654
Function
[CATS_MOUSE] Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L and cathepsin N.
About this Structure
4bs5 is a 1 chain structure with sequence from Lk3 transgenic mice. Full crystallographic information is available from OCA.
Reference
- Hilpert H, Mauser H, Humm R, Anselm L, Kuehne H, Hartmann G, Gruener S, Banner DW, Benz J, Gsell B, Kuglstatter A, Stihle M, Thoma R, Sanchez RA, Iding H, Wirz B, Haap W. Identification of Potent and Selective Cathepsin S Inhibitors Containing Different Central Cyclic Scaffolds. J Med Chem. 2013 Nov 22. PMID:24224654 doi:https://dx.doi.org/10.1021/jm401528k
