2qoa: Difference between revisions

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[[Image:2qoa.jpg|left|200px]]<br /><applet load="2qoa" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2qoa.jpg|left|200px]]
caption="2qoa, resolution 1.60&Aring;" />
 
'''Crystal structure of the complex of hcaii with an indane-sulfonamide inhibitor'''<br />
{{Structure
|PDB= 2qoa |SIZE=350|CAPTION= <scene name='initialview01'>2qoa</scene>, resolution 1.60&Aring;
|SITE= <scene name='pdbsite=AC1:Zn+Binding+Site+For+Residue+A+262'>AC1</scene>, <scene name='pdbsite=AC2:Cl+Binding+Site+For+Residue+A+263'>AC2</scene>, <scene name='pdbsite=AC3:Mbo+Binding+Site+For+Residue+A+264'>AC3</scene>, <scene name='pdbsite=AC4:Maj+Binding+Site+For+Residue+A+800'>AC4</scene>, <scene name='pdbsite=AC5:Maj+Binding+Site+For+Residue+A+801'>AC5</scene> and <scene name='pdbsite=AC6:Gol+Binding+Site+For+Residue+A+802'>AC6</scene>
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MBO:MERCURIBENZOIC+ACID'>MBO</scene>, <scene name='pdbligand=MAJ:'>MAJ</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Carbonate_dehydratase Carbonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.1 4.2.1.1]
|GENE=
}}
 
'''Crystal structure of the complex of hcaii with an indane-sulfonamide inhibitor'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2QOA is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=CL:'>CL</scene>, <scene name='pdbligand=MBO:'>MBO</scene>, <scene name='pdbligand=MAJ:'>MAJ</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Carbonate_dehydratase Carbonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.1 4.2.1.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QOA OCA].  
2QOA is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QOA OCA].  


==Reference==
==Reference==
Carbonic Anhydrase Inhibitors: Binding of Indanesulfonamides to the Human Isoform II., D'Ambrosio K, Masereel B, Thiry A, Scozzafava A, Supuran CT, De Simone G, ChemMedChem. 2007 Dec 27;. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=18161740 18161740]
Carbonic Anhydrase Inhibitors: Binding of Indanesulfonamides to the Human Isoform II., D'Ambrosio K, Masereel B, Thiry A, Scozzafava A, Supuran CT, De Simone G, ChemMedChem. 2007 Dec 27;. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18161740 18161740]
[[Category: Carbonate dehydratase]]
[[Category: Carbonate dehydratase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: lyase]]
[[Category: lyase]]


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