2qpp: Difference between revisions

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[[Image:2qpp.jpg|left|200px]]<br /><applet load="2qpp" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2qpp.jpg|left|200px]]
caption="2qpp, resolution 2.610&Aring;" />
 
'''Crystal structure of human heme oxygenase-2 C127A (HO-2) with bound heme'''<br />
{{Structure
|PDB= 2qpp |SIZE=350|CAPTION= <scene name='initialview01'>2qpp</scene>, resolution 2.610&Aring;
|SITE= <scene name='pdbsite=AC1:Hem+Binding+Site+For+Residue+A+300'>AC1</scene> and <scene name='pdbsite=AC2:Hem+Binding+Site+For+Residue+B+300'>AC2</scene>
|LIGAND= <scene name='pdbligand=HEM:PROTOPORPHYRIN IX CONTAINING FE'>HEM</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Heme_oxygenase Heme oxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.99.3 1.14.99.3]
|GENE= HMOX2, HO2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Crystal structure of human heme oxygenase-2 C127A (HO-2) with bound heme'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2QPP is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=HEM:'>HEM</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Heme_oxygenase Heme oxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.99.3 1.14.99.3] Known structural/functional Sites: <scene name='pdbsite=AC1:Hem+Binding+Site+For+Residue+A+300'>AC1</scene> and <scene name='pdbsite=AC2:Hem+Binding+Site+For+Residue+B+300'>AC2</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QPP OCA].  
2QPP is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QPP OCA].  


==Reference==
==Reference==
Comparison of apo- and heme-bound crystal structures of a truncated human heme oxygenase-2., Bianchetti CM, Yi L, Ragsdale SW, Phillips GN Jr, J Biol Chem. 2007 Dec 28;282(52):37624-31. Epub 2007 Oct 26. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17965015 17965015]
Comparison of apo- and heme-bound crystal structures of a truncated human heme oxygenase-2., Bianchetti CM, Yi L, Ragsdale SW, Phillips GN Jr, J Biol Chem. 2007 Dec 28;282(52):37624-31. Epub 2007 Oct 26. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17965015 17965015]
[[Category: Heme oxygenase]]
[[Category: Heme oxygenase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Wesenberg, G E.]]
[[Category: Wesenberg, G E.]]
[[Category: HEM]]
[[Category: HEM]]
[[Category: center for eukaryotic structural genomics]]
[[Category: center for eukaryotic structural genomic]]
[[Category: cesg]]
[[Category: cesg]]
[[Category: endoplasmic reticulum]]
[[Category: endoplasmic reticulum]]
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[[Category: structural genomics medical relevance]]
[[Category: structural genomics medical relevance]]


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