4m8o: Difference between revisions
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==About this Structure== | ==About this Structure== | ||
[[4m8o]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M8O OCA]. | [[4m8o]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M8O OCA]. | ||
==Reference== | ==Reference== | ||
<references group="xtra"/><references/> | <references group="xtra"/><references/> | ||
[[Category: Baker's yeast]] | |||
[[Category: DNA-directed DNA polymerase]] | [[Category: DNA-directed DNA polymerase]] | ||
[[Category: Hogg, M.]] | [[Category: Hogg, M.]] | ||
Revision as of 12:38, 11 December 2013
TERNARY COMPLEX OF DNA POLYMERASE EPSILON WITH AN INCOMING dATP
Function
[DPOE_YEAST] DNA polymerase epsilon (DNA polymerase II) participates in chromosomal DNA replication. It is required during synthesis of the leading and lagging DNA strands at the replication fork and binds at/or near replication origins and moves along DNA with the replication fork. It has 3'-5' proofreading exonuclease activity that correct errors arising during DNA replication. It is also involved in DNA synthesis during DNA repair.[1]
About this Structure
4m8o is a 3 chain structure with sequence from Baker's yeast. Full crystallographic information is available from OCA.
Reference
- ↑ Shimizu K, Hashimoto K, Kirchner JM, Nakai W, Nishikawa H, Resnick MA, Sugino A. Fidelity of DNA polymerase epsilon holoenzyme from budding yeast Saccharomyces cerevisiae. J Biol Chem. 2002 Oct 4;277(40):37422-9. Epub 2002 Jul 17. PMID:12124389 doi:https://dx.doi.org/10.1074/jbc.M204476200
