Sandbox Reserved 773: Difference between revisions

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== Implications ==  
== Implications ==  


Histamine is a key factor which relates to many physiological process. Some of these affected physiological process are listed below:  
Histamine is a key mediator which is associated with many physiological process including:
   
   
- Allegoric reaction and Inflammation response <ref name=dev>PMID: 18650915</ref>
- Allegoric reaction and Inflammation response <ref name=dev>PMID: 18650915</ref>
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- Gastric acid secretion <ref> PMID: 10461351</ref> <ref name=autoanti>PMID: 12679420</ref>
- Gastric acid secretion <ref> PMID: 10461351</ref> <ref name=autoanti>PMID: 12679420</ref>


- Capiliary dilation and smooth muscle contraction <ref name=dev/>
- Capillary dilation and smooth muscle contraction <ref name=dev/>


- Immune response <ref name=trend>PMID: 12102747</ref>
- Immune response <ref name=trend>PMID: 12102747</ref>


- Nuerotansmission in CNS <ref name=arousal>PMID:4011742</ref> <ref name=tour/>
- neurotansmission in CNS <ref name=arousal>PMID:4011742</ref> <ref name=tour/>




One of the most important role histamine play is the role of Neurotransmitter in the central nervous system (CNS). When HDC is inhibited to function, it can change histaminergic neuron mediated physiological response listed below, as well as contributes to the probability for multiple diseases:
One of the most important role histamine play is the role of neurotransmitter in the central nervous system (CNS). When HDC is inhibited to function, it can change histaminergic neuron mediated physiological response listed below, as well as contributes to the probability for multiple diseases:


- Arousal <ref name=arousal/> <ref name=sleep>PMID: 12196593</ref>
- Arousal <ref name=arousal/> <ref name=sleep>PMID: 12196593</ref>
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However outside of the central nervous system, anti-histamine drugs or HDC inhibitors are useful for treatment against allergic reaction, gastric ulcer, and inflammation <ref name=fun/> <ref name=jbc/>
However outside of the central nervous system, anti-histamine drugs or HDC inhibitors are useful for treatment against allergic reaction, gastric ulcer, and inflammation <ref name=fun/> <ref name=jbc/>


== References ==
== References ==
{{reflist}}
{{reflist}}
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