2qrc: Difference between revisions

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[[Image:2qrc.jpg|left|200px]]<br /><applet load="2qrc" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2qrc.jpg|left|200px]]
caption="2qrc, resolution 2.70&Aring;" />
 
'''Crystal structure of the adenylate sensor from AMP-activated protein kinase in complex with ADP and AMP'''<br />
{{Structure
|PDB= 2qrc |SIZE=350|CAPTION= <scene name='initialview01'>2qrc</scene>, resolution 2.70&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene> and <scene name='pdbligand=ADP:ADENOSINE-5'-DIPHOSPHATE'>ADP</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1]
|GENE= ssp2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4896 Schizosaccharomyces pombe])
}}
 
'''Crystal structure of the adenylate sensor from AMP-activated protein kinase in complex with ADP and AMP'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2QRC is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe] with <scene name='pdbligand=AMP:'>AMP</scene> and <scene name='pdbligand=ADP:'>ADP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QRC OCA].  
2QRC is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QRC OCA].  


==Reference==
==Reference==
Structural insight into AMPK regulation: ADP comes into play., Jin X, Townley R, Shapiro L, Structure. 2007 Oct;15(10):1285-95. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17937917 17937917]
Structural insight into AMPK regulation: ADP comes into play., Jin X, Townley R, Shapiro L, Structure. 2007 Oct;15(10):1285-95. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17937917 17937917]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Protein complex]]
[[Category: Protein complex]]
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[[Category: transferase]]
[[Category: transferase]]


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