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==Histidinol Dehydrogenase==
==Histidinol Dehydrogenase==


Histidinol dehydrogenase (HDH) is an enzyme coded by the structural gene hisD.  HDH catalyzes the last step in the histidine biosynthetic pathway.  This primordial pathway was found in bacteria, archaebacteria, fungi, and plants.  hiD catalyzes the last step in the biosynthetic pathway of histidine, which causes the conversion of L-histidinol to L-histidine with a L-histidinaldehyde intermediate <ref name="pnas">http://www.pnas.org.prox.lib.ncsu.edu/content/99/4/1859.full.pdf</ref>
Histidinol dehydrogenase (HDH) is an enzyme coded by the structural gene hisD.  HDH catalyzes the last step in the histidine biosynthetic pathway.  This primordial pathway was found in bacteria, archaebacteria, fungi, and plants.  The catalyzation of the last step in the biosynthetic pathway of histidine, causes the conversion of L-histidinol to L-histidine with a L-histidinaldehyde intermediate <ref name="pnas">http://www.pnas.org.prox.lib.ncsu.edu/content/99/4/1859.full.pdf</ref>