2qv6: Difference between revisions

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[[Image:2qv6.jpg|left|200px]]<br /><applet load="2qv6" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2qv6.jpg|left|200px]]
caption="2qv6, resolution 2.00&Aring;" />
 
'''GTP cyclohydrolase III from M. jannaschii (MJ0145) complexed with GTP and metal ions'''<br />
{{Structure
|PDB= 2qv6 |SIZE=350|CAPTION= <scene name='initialview01'>2qv6</scene>, resolution 2.00&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene> and <scene name='pdbligand=GTP:GUANOSINE-5'-TRIPHOSPHATE'>GTP</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/GTP_cyclohydrolase_IIa GTP cyclohydrolase IIa], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.4.29 3.5.4.29]
|GENE= gch3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2190 Methanocaldococcus jannaschii])
}}
 
'''GTP cyclohydrolase III from M. jannaschii (MJ0145) complexed with GTP and metal ions'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2QV6 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii] with <scene name='pdbligand=K:'>K</scene>, <scene name='pdbligand=CA:'>CA</scene>, <scene name='pdbligand=NA:'>NA</scene> and <scene name='pdbligand=GTP:'>GTP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/GTP_cyclohydrolase_IIa GTP cyclohydrolase IIa], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.4.29 3.5.4.29] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QV6 OCA].  
2QV6 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QV6 OCA].  


==Reference==
==Reference==
A new use for a familiar fold: the X-ray crystal structure of GTP-bound GTP cyclohydrolase III from Methanocaldococcus jannaschii reveals a two metal ion catalytic mechanism., Morrison SD, Roberts SA, Zegeer AM, Montfort WR, Bandarian V, Biochemistry. 2008 Jan 8;47(1):230-42. Epub 2007 Dec 4. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=18052207 18052207]
A new use for a familiar fold: the X-ray crystal structure of GTP-bound GTP cyclohydrolase III from Methanocaldococcus jannaschii reveals a two metal ion catalytic mechanism., Morrison SD, Roberts SA, Zegeer AM, Montfort WR, Bandarian V, Biochemistry. 2008 Jan 8;47(1):230-42. Epub 2007 Dec 4. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18052207 18052207]
[[Category: GTP cyclohydrolase IIa]]
[[Category: GTP cyclohydrolase IIa]]
[[Category: Methanocaldococcus jannaschii]]
[[Category: Methanocaldococcus jannaschii]]
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[[Category: hydrolase]]
[[Category: hydrolase]]


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