2r0o: Difference between revisions

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[[Image:2r0o.jpg|left|200px]]<br /><applet load="2r0o" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2r0o.jpg|left|200px]]
caption="2r0o, resolution 2.20&Aring;" />
 
'''Crystal structure of the actin-binding domain of human alpha-actinin-4 mutant(K255E)'''<br />
{{Structure
|PDB= 2r0o |SIZE=350|CAPTION= <scene name='initialview01'>2r0o</scene>, resolution 2.20&Aring;
|SITE= <scene name='pdbsite=AC1:Gol+Binding+Site+For+Residue+A+1'>AC1</scene>, <scene name='pdbsite=AC2:Gol+Binding+Site+For+Residue+B+2'>AC2</scene> and <scene name='pdbsite=AC3:Gol+Binding+Site+For+Residue+B+3'>AC3</scene>
|LIGAND= <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
|ACTIVITY=
|GENE= ACTN4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Crystal structure of the actin-binding domain of human alpha-actinin-4 mutant(K255E)'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2R0O is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Known structural/functional Sites: <scene name='pdbsite=AC1:Gol+Binding+Site+For+Residue+A+1'>AC1</scene>, <scene name='pdbsite=AC2:Gol+Binding+Site+For+Residue+B+2'>AC2</scene> and <scene name='pdbsite=AC3:Gol+Binding+Site+For+Residue+B+3'>AC3</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R0O OCA].  
2R0O is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R0O OCA].  


==Reference==
==Reference==
Crystal structure of the actin-binding domain of alpha-actinin-4 Lys255Glu mutant implicated in focal segmental glomerulosclerosis., Lee SH, Weins A, Hayes DB, Pollak MR, Dominguez R, J Mol Biol. 2008 Feb 15;376(2):317-24. Epub 2007 Dec 4. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=18164029 18164029]
Crystal structure of the actin-binding domain of alpha-actinin-4 Lys255Glu mutant implicated in focal segmental glomerulosclerosis., Lee SH, Weins A, Hayes DB, Pollak MR, Dominguez R, J Mol Biol. 2008 Feb 15;376(2):317-24. Epub 2007 Dec 4. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18164029 18164029]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: structural protein]]
[[Category: structural protein]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:43:47 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:31:29 2008''