4nob: Difference between revisions
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==Crystal structure of the 1st Ig domain from mouse Polymeric Immunoglobulin receptor [PSI-NYSGRC-006220]== | |||
<StructureSection load='4nob' size='340' side='right' caption='[[4nob]], [[Resolution|resolution]] 1.51Å' scene=''> | |||
== Structural highlights == | |||
==Function== | <table><tr><td colspan='2'>[[4nob]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NOB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4NOB FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | |||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Pigr ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4nob FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nob OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4nob RCSB], [http://www.ebi.ac.uk/pdbsum/4nob PDBsum]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/PIGR_MOUSE PIGR_MOUSE]] This receptor binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment (By similarity). | [[http://www.uniprot.org/uniprot/PIGR_MOUSE PIGR_MOUSE]] This receptor binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment (By similarity). | ||
__TOC__ | |||
</StructureSection> | |||
[[ | [[Category: Lk3 transgenic mice]] | ||
[[Category: Almo, S C | [[Category: Almo, S C]] | ||
[[Category: Attonito, J | [[Category: Attonito, J]] | ||
[[Category: Banu, R | [[Category: Banu, R]] | ||
[[Category: Bhosle, R | [[Category: Bhosle, R]] | ||
[[Category: Calarese, D A | [[Category: Calarese, D A]] | ||
[[Category: Casadevall, A | [[Category: Casadevall, A]] | ||
[[Category: Celikgil, A | [[Category: Celikgil, A]] | ||
[[Category: Chamala, S | [[Category: Chamala, S]] | ||
[[Category: Chan, M K | [[Category: Chan, M K]] | ||
[[Category: Chowdhury, S | [[Category: Chowdhury, S]] | ||
[[Category: Fiser, A | [[Category: Fiser, A]] | ||
[[Category: Garforth, S J | [[Category: Garforth, S J]] | ||
[[Category: Glenn, A S | [[Category: Glenn, A S]] | ||
[[Category: Hillerich, B | [[Category: Hillerich, B]] | ||
[[Category: IFN, Atoms-to-Animals:.The Immune Function Network | [[Category: IFN, Atoms-to-Animals:.The Immune Function Network]] | ||
[[Category: Khafizov, K | [[Category: Khafizov, K]] | ||
[[Category: Kumar, P R | [[Category: Kumar, P R]] | ||
[[Category: Love, J D | [[Category: Love, J D]] | ||
[[Category: | [[Category: Structural genomic]] | ||
[[Category: Patel, H | [[Category: Patel, H]] | ||
[[Category: Patel, R | [[Category: Patel, R]] | ||
[[Category: Seidel, R D | [[Category: Seidel, R D]] | ||
[[Category: Smith, B | [[Category: Smith, B]] | ||
[[Category: Stead, M | [[Category: Stead, M]] | ||
[[Category: Ifn]] | [[Category: Ifn]] | ||
[[Category: Ig domain]] | [[Category: Ig domain]] | ||
[[Category: Immune function network]] | [[Category: Immune function network]] | ||
[[Category: Immune system]] | [[Category: Immune system]] | ||
[[Category: Nysgrc]] | [[Category: Nysgrc]] | ||
[[Category: Ortholog]] | [[Category: Ortholog]] | ||
[[Category: Psi-biology]] | [[Category: Psi-biology]] | ||
