2r40: Difference between revisions

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[[Image:2r40.gif|left|200px]]<br /><applet load="2r40" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2r40.gif|left|200px]]
caption="2r40, resolution 2.402&Aring;" />
 
'''Crystal structure of 20E bound EcR/USP'''<br />
{{Structure
|PDB= 2r40 |SIZE=350|CAPTION= <scene name='initialview01'>2r40</scene>, resolution 2.402&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=20E:(2beta,3beta,5beta,22R)-2,3,14,20,22,25-hexahydroxycholest-7-en-6-one'>20E</scene>, <scene name='pdbligand=EPH:L-ALPHA-PHOSPHATIDYL-BETA-OLEOYL-GAMMA-PALMITOYL-PHOSPHATIDYLETHANOLAMINE'>EPH</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
|ACTIVITY=
|GENE= EcR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7102 Heliothis virescens])
}}
 
'''Crystal structure of 20E bound EcR/USP'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2R40 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Heliothis_virescens Heliothis virescens] with <scene name='pdbligand=FLC:'>FLC</scene>, <scene name='pdbligand=SO4:'>SO4</scene>, <scene name='pdbligand=20E:'>20E</scene>, <scene name='pdbligand=EPH:'>EPH</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R40 OCA].  
2R40 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Heliothis_virescens Heliothis virescens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R40 OCA].  


==Reference==
==Reference==
Critical role of desolvation in the binding of 20-hydroxyecdysone to the ecdysone receptor., Browning C, Martin E, Loch C, Wurtz JM, Moras D, Stote RH, Dejaegere AP, Billas IM, J Biol Chem. 2007 Nov 9;282(45):32924-34. Epub 2007 Sep 11. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17848566 17848566]
Critical role of desolvation in the binding of 20-hydroxyecdysone to the ecdysone receptor., Browning C, Martin E, Loch C, Wurtz JM, Moras D, Stote RH, Dejaegere AP, Billas IM, J Biol Chem. 2007 Nov 9;282(45):32924-34. Epub 2007 Sep 11. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17848566 17848566]
[[Category: Heliothis virescens]]
[[Category: Heliothis virescens]]
[[Category: Protein complex]]
[[Category: Protein complex]]
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[[Category: nuclear receptor ligand-binding domain]]
[[Category: nuclear receptor ligand-binding domain]]


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