Sandbox Reserved 765: Difference between revisions
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Contagious diseases are increasingly becoming a major public health issue. The shikimate pathway is often used for the advancement of antimicrobial mixures to fight against these diseases. This process only takes place in prokaryotes, fungi and plants. '''Chorismate synthase''' is the enzyme that is used in the shikimate pathway, which catalyzes the coversion of phosphoenol pyruvate to chorismate. Chorismate Synthase is an enzyme part of the lyase family. Studying this enzyme and the roles that it plays in many diseases, inhibition of this reaction can lead to oral treatment for infectious diseases and further growth. This enzyme is responsible for catalyzing the following reversible reaction: | Contagious diseases are increasingly becoming a major public health issue. The shikimate pathway is often used for the advancement of antimicrobial mixures to fight against these diseases. This process only takes place in prokaryotes, fungi and plants <ref>PMID:3670998</ref>. '''Chorismate synthase''' is the enzyme that is used in the shikimate pathway, which catalyzes the coversion of phosphoenol pyruvate to chorismate. Chorismate Synthase is an enzyme part of the lyase family. Choirsmate is used as a precursor to make the following proteins: L-tyrosine, L-phenylalanine, and L-tryptophan. Studying this enzyme and the roles that it plays in many diseases, inhibition of this reaction can lead to oral treatment for infectious diseases and further growth. This enzyme is responsible for catalyzing the following reversible reaction: | ||
5-enolpyruvylshikimate-3-phosphate <--> Chorismate + Phosphate. | 5-enolpyruvylshikimate-3-phosphate <--> Chorismate + Phosphate. | ||
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voerijffoiejffoi | voerijffoiejffoi | ||
veiprvmeripvmrepiom | veiprvmeripvmrepiom | ||
==Implications== | |||
The implications with studying choristmate synthase revolves around the fact that it isn not present in humans but is essential for bacteria, plants and parasites. This pathway gives rise to many potential antimicrobial drugs which decreases possible negative impacts of drugs in humans. | |||
==References== | |||
{{reflist}} | |||
</StructureSection> | </StructureSection> | ||
