Sandbox Reserved 769: Difference between revisions

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	Indole-3-glycerol-phosphate (IGP) is cleaved by the tryptophan synthase α-subunit (TSA) to indole and glyceraldehyde-3-phosphate (GDP) This is known as the α-reaction. The alpha reaction is reversible. Then indole is transported via a 30 Å intermolecular tunnel to the tryptophan synthase β-subunits (TSB) that catalyze the condensation of indole and serine to tryptophan. This is known as the β-reaction and it is a pyridoxal-5-phosphate (PLP) dependent reaction.		Indole-3-glycerol-phosphate (IGP) is cleaved by the tryptophan synthase α-subunit (TSA) to indole and glyceraldehyde-3-phosphate (GDP) This is known as the α-reaction. The alpha reaction is reversible. Then indole is transported via a 30 Å intermolecular tunnel to the tryptophan synthase β-subunits (TSB) that catalyze the condensation of indole and serine to tryptophan. This is known as the β-reaction and it is a pyridoxal-5-phosphate (PLP) dependent reaction. <ref name="cite7">http://tryptophan.net/Trpsynthase/Tryptophan%20Synthase.html</ref>



	[[Image:TrpSyn.gif]]		[[Image:TrpSyn.gif]]

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