Sandbox Reserved 766: Difference between revisions
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'''Asparagine Synthetase''' (ASNS) is an enzyme that catalyzes the conversion of Aspartic Acid to Asparagine through an ATP dependent amination reaction, using Mg2+ as a cofactor. ASNS can be found in both plants and mammals, however, in plants there are two forms ASNS-A and ASNS-B. Both forms use the same starting molecule of Aspartic Acid and produce Asparagine, the only difference coming from the source of the Nitrogen. ASNS-A uses inorganic Nitrogen in the form of | '''Asparagine Synthetase''' (ASNS) is an enzyme that catalyzes the conversion of Aspartic Acid to Asparagine through an ATP dependent amination reaction, using Mg2+ as a cofactor. ASNS can be found in both plants and mammals, however, in plants there are two forms ASNS-A and ASNS-B. Both forms use the same starting molecule of Aspartic Acid and produce Asparagine, the only difference coming from the source of the Nitrogen. ASNS-A uses inorganic Nitrogen in the form of ammonia or diatomic Nitrogen and ASNS-B uses Glutamine as its Nitrogen source; ASNS-B will be the focus of this page because it is very similar and undergoes the same reaction as ASNS in mammals. | ||
== Structure == | == Structure == | ||