Sandbox Reserved 766: Difference between revisions

<scene name='56/564042/Glutamine_amidotransferase/1'>Glutamine Amidotransferase Type-2</scene> (residues 2-191) and and <scene name='56/564042/Asparagine_synthetase_complex/1'>Asparagine Synthetase</scene> complex (residues 213-536). There are two specific domains that contain the substrate binding sites. The N-terminal domain which contains two layers of anti-parallel beta sheets comprised of six layers each, this is where the Glutamine binds. A C-terminal domain also exists, it is comprised of five parallel beta sheets with alpha helices on either side of it, <ref>"RCSB Protein Data Bank - RCSB PDB - 1CT9 Structure Summary." RCSB Protein Data Bank - RCSB PDB - 1CT9 Structure Summary. N.p., n.d. Web. 01 Dec. 2013.</ref> this is where the Mg2+, ATP and Aspartic Acid bind. The two active sites contained within the terminal domains are linked together by a tunnel of hydrophobic and polar surface amino acid residues. Specifically <scene name='56/564042/Residue_365/1'>Residue 365</scene> is important for the binding of the Beta-Asparty-AMP intermediate into the enzyme.