Sandbox Reserved 766: Difference between revisions
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===Ovarian Cancer Predictive Bio-Marker=== | ===Ovarian Cancer Predictive Bio-Marker=== | ||
Recent studies have been trying to find a potential link between the amount of ASNS activity in certain cell cultures as a precursor for L-Asparaginase activity. L-Asparaginase is an enzyme that degrades Asparagine and has been used since the 1970's in basic cancer treatment plans for acute lymphoblastic leukemia | Recent studies have been trying to find a potential link between the amount of ASNS activity in certain cell cultures as a precursor for L-Asparaginase activity. L-Asparaginase is an enzyme that degrades Asparagine and has been used since the 1970's in basic cancer treatment plans for acute lymphoblastic leukemia.<ref>"Asparagine Synthetase as a Causal, Predictive Biomarker for L-asparaginase Activity in Ovarian Cancer Cells." Asparagine Synthetase as a Causal, Predictive Biomarker for L-asparaginase Activity in Ovarian Cancer Cells. N.p., n.d. Web. 02 Dec. 2013.</ref>The body will naturally secrete L-Asparaginase as a response to a potential forming tumor or potential cancer cell aggregation. These studies are finding a correlation between the amount of ASNS being expressed prior to the expression of L-Asparaginase synthetase,<ref>"Asparagine Synthetase as a Causal, Predictive Biomarker for L-asparaginase Activity in Ovarian Cancer Cells." Asparagine Synthetase as a Causal, Predictive Biomarker for L-asparaginase Activity in Ovarian Cancer Cells. N.p., n.d. Web. 02 Dec. 2013.</ref> since L-Asparaginase has only been shown to help combat lymphoblastic leukemia this would not be a direct treatment but rather an indicator that something is happening that requires attention and hopefully allow doctors to screen for ASNS activity and catch ovarian cancer in it's earlier stages when it is more treatable and easier to remove from the body. | ||
==References== | ==References== | ||