4c64: Difference between revisions
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==ULTRA HIGH RESOLUTION DICKERSON-DREW DODECAMER B-DNA== | |||
<StructureSection load='4c64' size='340' side='right' caption='[[4c64]], [[Resolution|resolution]] 1.32Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4c64]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C64 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4C64 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4c5x|4c5x]], [[4c63|4c63]]</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4c64 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4c64 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4c64 RCSB], [http://www.ebi.ac.uk/pdbsum/4c64 PDBsum]</span></td></tr> | |||
</table> | |||
<div style="background-color:#fffaf0;"> | |||
== Publication Abstract from PubMed == | |||
Transcription factor binding and high resolution crystallographic studies (1.3 A) of Dickerson-Drew duplexes with cytosine, methylcytosine and hydroxymethylcytosine bases provide evidence that C-5 cytosine modifications could regulate transcription by context dependent effects on DNA transcription factor interactions. | |||
Structural insights into how 5-hydroxymethylation influences transcription factor binding.,Lercher L, McDonough MA, El-Sagheer AH, Thalhammer A, Kriaucionis S, Brown T, Schofield CJ Chem Commun (Camb). 2013 Nov 29. PMID:24287551<ref>PMID:24287551</ref> | |||
== | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | |||
[[Category: Brown, T | == References == | ||
[[Category: El-Sagheer, A H | <references/> | ||
[[Category: Mcdonough, M | __TOC__ | ||
[[Category: Schofield, C J | </StructureSection> | ||
[[Category: Brown, T]] | |||
[[Category: El-Sagheer, A H]] | |||
[[Category: Mcdonough, M]] | |||
[[Category: Schofield, C J]] | |||
[[Category: Dna]] | [[Category: Dna]] | ||
Revision as of 14:26, 4 January 2015
ULTRA HIGH RESOLUTION DICKERSON-DREW DODECAMER B-DNA
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