4c8d: Difference between revisions

Line 1:

~~{{STRUCTURE_4c8d| PDB=4c8d | SCENE= }}~~

==Crystal structure of JmjC domain of human histone 3 Lysine-specific demethylase 3B (KDM3B)==

===Crystal structure of JmjC domain of human histone 3 Lysine-specific demethylase 3B (KDM3B)===

== Structural highlights ==

==Function==

<table><tr><td colspan='2'>[[4c8d]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C8D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4C8D FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=OGA:N-OXALYLGLYCINE'>OGA</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4c8d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4c8d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4c8d RCSB], [http://www.ebi.ac.uk/pdbsum/4c8d PDBsum]</span></td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/KDM3B_HUMAN KDM3B_HUMAN]] Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity.<ref>PMID:16603237</ref>

== References ==

==~~About this Structure==~~

[[4c8d]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C8D OCA].

__TOC__

</StructureSection>

~~==Reference~~==

[[Category: Human]]

[[Category: Arrowsmith, C H.]]

[[Category: Arrowsmith, C H]]

[[Category: Bountra, C.]]

[[Category: Bountra, C]]

[[Category: Crawley, L.]]

[[Category: Crawley, L]]

[[Category: Delft, F von.]]

[[Category: Delft, F von]]

[[Category: Edwards, A.]]

[[Category: Edwards, A]]

[[Category: Gileadi, C.]]

[[Category: Gileadi, C]]

[[Category: Goubin, S.]]

[[Category: Goubin, S]]

[[Category: Johansson, C.]]

[[Category: Johansson, C]]

[[Category: Krojer, T.]]

[[Category: Krojer, T]]

[[Category: Oppermann, U.]]

[[Category: Oppermann, U]]

[[Category: Szykowska, A.]]

[[Category: Szykowska, A]]

[[Category: Vollmar, M.]]

[[Category: Vollmar, M]]

[[Category: Oxidoreductase]]

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@@ Line 1: / Line 1: @@
-{{STRUCTURE_4c8d|  PDB=4c8d  |  SCENE=  }}
+==Crystal structure of JmjC domain of human histone 3 Lysine-specific demethylase 3B (KDM3B)==
-===Crystal structure of JmjC domain of human histone 3 Lysine-specific demethylase 3B (KDM3B)===
+<StructureSection load='4c8d' size='340' side='right' caption='[[4c8d]], [[Resolution|resolution]] 2.18&Aring;' scene=''>
+== Structural highlights ==
-==Function==
+<table><tr><td colspan='2'>[[4c8d]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C8D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4C8D FirstGlance]. <br>
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=OGA:N-OXALYLGLYCINE'>OGA</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4c8d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4c8d OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4c8d RCSB], [http://www.ebi.ac.uk/pdbsum/4c8d PDBsum]</span></td></tr>
+</table>
+== Function ==
 [[http://www.uniprot.org/uniprot/KDM3B_HUMAN KDM3B_HUMAN]] Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity.<ref>PMID:16603237</ref>
+== References ==
-==About this Structure==
+<references/>
-[[4c8d]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C8D OCA].
+__TOC__
+</StructureSection>
-==Reference==
-<references group="xtra"/><references/>
 [[Category: Human]]
-[[Category: Arrowsmith, C H.]]
+[[Category: Arrowsmith, C H]]
-[[Category: Bountra, C.]]
+[[Category: Bountra, C]]
-[[Category: Crawley, L.]]
+[[Category: Crawley, L]]
-[[Category: Delft, F von.]]
+[[Category: Delft, F von]]
-[[Category: Edwards, A.]]
+[[Category: Edwards, A]]
-[[Category: Gileadi, C.]]
+[[Category: Gileadi, C]]
-[[Category: Goubin, S.]]
+[[Category: Goubin, S]]
-[[Category: Johansson, C.]]
+[[Category: Johansson, C]]
-[[Category: Krojer, T.]]
+[[Category: Krojer, T]]
-[[Category: Oppermann, U.]]
+[[Category: Oppermann, U]]
-[[Category: Szykowska, A.]]
+[[Category: Szykowska, A]]
-[[Category: Vollmar, M.]]
+[[Category: Vollmar, M]]
 [[Category: Oxidoreductase]]