4np9: Difference between revisions
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{{STRUCTURE_4np9| PDB=4np9 | SCENE= }} | |||
===Structure of Rabphilin C2A domain bound to IP3=== | |||
{{ABSTRACT_PUBMED_24302762}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/RP3A_RAT RP3A_RAT]] Protein transport. Probably involved with Ras-related protein Rab-3A in synaptic vesicle traffic and/or synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal. | |||
==About this Structure== | |||
[[4np9]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NP9 OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:024302762</ref><references group="xtra"/><references/> | |||
[[Category: Buxaderas, M.]] | |||
[[Category: Corbalan-Garcia, S.]] | |||
[[Category: Ferrer-Orta, C.]] | |||
[[Category: Gomez-Fernandez, J C.]] | |||
[[Category: Guerra, P.]] | |||
[[Category: Guerrero-Valero, M.]] | |||
[[Category: Guillen, J.]] | |||
[[Category: Luengo-Gil, G.]] | |||
[[Category: Perez-Sanchez, D.]] | |||
[[Category: Pous, J.]] | |||
[[Category: Verdaguer, N.]] | |||
[[Category: C-2 domain fold]] | |||
[[Category: C2 domain]] | |||
[[Category: C2a]] | |||
[[Category: Calcium binding]] | |||
[[Category: Exophilin-1]] | |||
[[Category: Protein transport]] | |||
[[Category: Rabphilin-3a]] | |||
[[Category: Synaptic exocytosis metal-binding]] | |||
Revision as of 10:19, 25 December 2013
Structure of Rabphilin C2A domain bound to IP3
Template:ABSTRACT PUBMED 24302762
Function
[RP3A_RAT] Protein transport. Probably involved with Ras-related protein Rab-3A in synaptic vesicle traffic and/or synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal.
About this Structure
4np9 is a 1 chain structure. Full crystallographic information is available from OCA.
Reference
- Guillen J, Ferrer-Orta C, Buxaderas M, Perez-Sanchez D, Guerrero-Valero M, Luengo-Gil G, Pous J, Guerra P, Gomez-Fernandez JC, Verdaguer N, Corbalan-Garcia S. Structural insights into the Ca2+ and PI(4,5)P2 binding modes of the C2 domains of rabphilin 3A and synaptotagmin 1. Proc Natl Acad Sci U S A. 2013 Dec 17;110(51):20503-8. doi:, 10.1073/pnas.1316179110. Epub 2013 Dec 3. PMID:24302762 doi:https://dx.doi.org/10.1073/pnas.1316179110
