4npp: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4npp|  PDB=4npp  |  SCENE=  }}
===The GLIC-His10 wild-type structure in equilibrium between the open and locally-closed (LC) forms===


The entry 4npp is ON HOLD
==Function==
[[http://www.uniprot.org/uniprot/GLIC_GLOVI GLIC_GLOVI]] Cationic channel with similar permeabilities for Na(+) and K(+), that is activated by an increase of the proton concentration on the extracellular side. Displays no permeability for chloride ions. Shows slow kinetics of activation, no desensitization and a single channel conductance of 8 pS. Might contribute to adaptation to external pH change.<ref>PMID:17167423</ref> 


Authors: Sauguet, L., Shahsavar, A, Poitevin, F., Huon, C., Menny, A., Nemecz, A., Haouz, A., Changeux, J.P., Corringer, P.J., Delarue, M.
==About this Structure==
[[4npp]] is a 5 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NPP OCA].  


Description: The GLIC-His10 wild-type structure in equilibrium between the open and locally-closed (LC) forms
==Reference==
<references group="xtra"/><references/>
[[Category: Changeux, J P.]]
[[Category: Corringer, P J.]]
[[Category: Delarue, M.]]
[[Category: Haouz, A.]]
[[Category: Huon, C.]]
[[Category: Menny, A.]]
[[Category: Nemecz, A.]]
[[Category: Poitevin, F.]]
[[Category: Sauguet, L.]]
[[Category: Shahsavar, A]]
[[Category: Pentameric ligand-gated ion channel]]
[[Category: Ph-gated]]
[[Category: Transmembrane]]
[[Category: Transport protein]]