2rfi: Difference between revisions
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[[Image:2rfi.jpg|left|200px]] | [[Image:2rfi.jpg|left|200px]] | ||
'''Crystal structure of catalytic domain of human euchromatic histone methyltransferase 1 in complex with SAH and dimethylated H3K9 peptide''' | {{Structure | ||
|PDB= 2rfi |SIZE=350|CAPTION= <scene name='initialview01'>2rfi</scene>, resolution 1.59Å | |||
|SITE= | |||
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> and <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene> | |||
|ACTIVITY= [http://en.wikipedia.org/wiki/Histone-lysine_N-methyltransferase Histone-lysine N-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.43 2.1.1.43] | |||
|GENE= EHMT1, EUHMTASE1, KIAA1876 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | |||
}} | |||
'''Crystal structure of catalytic domain of human euchromatic histone methyltransferase 1 in complex with SAH and dimethylated H3K9 peptide''' | |||
==Disease== | ==Disease== | ||
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==About this Structure== | ==About this Structure== | ||
2RFI is a [ | 2RFI is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RFI OCA]. | ||
[[Category: Histone-lysine N-methyltransferase]] | [[Category: Histone-lysine N-methyltransferase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: s-adenosyl-l-methionine]] | [[Category: s-adenosyl-l-methionine]] | ||
[[Category: sgc]] | [[Category: sgc]] | ||
[[Category: structural | [[Category: structural genomic]] | ||
[[Category: structural genomics consortium]] | [[Category: structural genomics consortium]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:35:35 2008'' | ||
Revision as of 16:35, 20 March 2008
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| 2rfi, resolution 1.59Å | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Ligands: | ZN and SAH | ||||||||||||
| Gene: | EHMT1, EUHMTASE1, KIAA1876 (Homo sapiens) | ||||||||||||
| Activity: | Histone-lysine N-methyltransferase, with EC number 2.1.1.43 | ||||||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||||||
Crystal structure of catalytic domain of human euchromatic histone methyltransferase 1 in complex with SAH and dimethylated H3K9 peptide
Disease
Known diseases associated with this structure: Chromosome 9q subtelomeric deletion syndrome OMIM:[607001]
About this Structure
2RFI is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Page seeded by OCA on Thu Mar 20 18:35:35 2008
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Histone-lysine N-methyltransferase
- Homo sapiens
- Protein complex
- Arrowsmith, C H.
- Bochkarev, A.
- Edwards, A M.
- Loppnau, P.
- Min, J.
- Plotnikov, A N.
- SGC, Structural Genomics Consortium.
- Sundstrom, M.
- Weigelt, J.
- Wu, H.
- SAH
- ZN
- Acetylation
- Alternative splicing
- Ank repeat
- Chromatin regulator
- Chromosomal protein
- Dna damage
- Dna repair
- Dna-binding
- Euchromatic histone methyltransferase 1
- Methylation
- Nucleosome core
- Nucleus
- Phosphorylation
- Polymorphism
- S-adenosyl-l-methionine
- Sgc
- Structural genomic
- Structural genomics consortium
