4nud: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4nud|  PDB=4nud  |  SCENE=  }}
===Crystal structure of the first bromodomain of human BRD4 in complex with MS436 inhibitor===
{{ABSTRACT_PUBMED_24144283}}


The entry 4nud is ON HOLD
==Disease==
[[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Note=A chromosomal aberration involving BRD4 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with NUT which produces a BRD4-NUT fusion protein.<ref>PMID:12543779</ref> <ref>PMID:11733348</ref> 


Authors: Plotnikov, A.N., Joshua, J., Zhou, M.-M.
==Function==
[[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity).  


Description: Crystal structure of the first bromodomain of human BRD4 in complex with MS436 inhibitor
==About this Structure==
[[4nud]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NUD OCA].
 
==Reference==
<ref group="xtra">PMID:024144283</ref><references group="xtra"/><references/>
[[Category: Joshua, J.]]
[[Category: Plotnikov, A N.]]
[[Category: Zhou, M M.]]
[[Category: Transcription]]
[[Category: Transcription factor]]
[[Category: Transcription-transcription inhibitor complex]]