2rfs: Difference between revisions

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[[Image:2rfs.jpg|left|200px]]<br /><applet load="2rfs" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2rfs.jpg|left|200px]]
caption="2rfs, resolution 2.20&Aring;" />
 
'''X-ray structure of SU11274 bound to c-Met'''<br />
{{Structure
|PDB= 2rfs |SIZE=350|CAPTION= <scene name='initialview01'>2rfs</scene>, resolution 2.20&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=AM8:N-(3-chlorophenyl)-N-methyl-2-oxo-3-[(3,4,5-trimethyl-1H-pyrrol-2-yl)methyl]-2H-indole-5-sulfonamide'>AM8</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1]
|GENE= MET ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''X-ray structure of SU11274 bound to c-Met'''
 


==Disease==
==Disease==
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==About this Structure==
==About this Structure==
2RFS is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=AM8:'>AM8</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RFS OCA].  
2RFS is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RFS OCA].  
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Receptor protein-tyrosine kinase]]
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[[Category: tyrosine-protein kinase]]
[[Category: tyrosine-protein kinase]]


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