2sim: Difference between revisions

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[[Image:2sim.gif|left|200px]]<br /><applet load="2sim" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2sim.gif|left|200px]]
caption="2sim, resolution 1.6&Aring;" />
 
'''THE STRUCTURES OF SALMONELLA TYPHIMURIUM LT2 NEURAMINIDASE AND ITS COMPLEX WITH A TRANSITION STATE ANALOGUE AT 1.6 ANGSTROMS RESOLUTION'''<br />
{{Structure
|PDB= 2sim |SIZE=350|CAPTION= <scene name='initialview01'>2sim</scene>, resolution 1.6&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=DAN:2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID'>DAN</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Exo-alpha-sialidase Exo-alpha-sialidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.18 3.2.1.18]
|GENE= PSX62 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=602 Salmonella typhimurium])
}}
 
'''THE STRUCTURES OF SALMONELLA TYPHIMURIUM LT2 NEURAMINIDASE AND ITS COMPLEX WITH A TRANSITION STATE ANALOGUE AT 1.6 ANGSTROMS RESOLUTION'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2SIM is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Salmonella_typhimurium Salmonella typhimurium] with <scene name='pdbligand=DAN:'>DAN</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. This structure supersedes the now removed PDB entry 1SIM. Active as [http://en.wikipedia.org/wiki/Exo-alpha-sialidase Exo-alpha-sialidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.18 3.2.1.18] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2SIM OCA].  
2SIM is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Salmonella_typhimurium Salmonella typhimurium]. This structure supersedes the now removed PDB entry 1SIM. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2SIM OCA].  


==Reference==
==Reference==
The structures of Salmonella typhimurium LT2 neuraminidase and its complexes with three inhibitors at high resolution., Crennell SJ, Garman EF, Philippon C, Vasella A, Laver WG, Vimr ER, Taylor GL, J Mol Biol. 1996 Jun 7;259(2):264-80. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=8656428 8656428]
The structures of Salmonella typhimurium LT2 neuraminidase and its complexes with three inhibitors at high resolution., Crennell SJ, Garman EF, Philippon C, Vasella A, Laver WG, Vimr ER, Taylor GL, J Mol Biol. 1996 Jun 7;259(2):264-80. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8656428 8656428]
[[Category: Exo-alpha-sialidase]]
[[Category: Exo-alpha-sialidase]]
[[Category: Salmonella typhimurium]]
[[Category: Salmonella typhimurium]]
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[[Category: hydrolase]]
[[Category: hydrolase]]


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