4ci8: Difference between revisions

Revision as of 09:50, 16 April 2014

[EMAL1_HUMAN] May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic (By similarity).

4ci8 is a 2 chain structure. Full crystallographic information is available from OCA.

Richards MW, Law EW, Rennalls LP, Busacca S, O'Regan L, Fry AM, Fennell DA, Bayliss R. Crystal structure of EML1 reveals the basis for Hsp90 dependence of oncogenic EML4-ALK by disruption of an atypical beta-propeller domain. Proc Natl Acad Sci U S A. 2014 Apr 8;111(14):5195-200. doi:, 10.1073/pnas.1322892111. Epub 2014 Mar 24. PMID:24706829 doi:https://dx.doi.org/10.1073/pnas.1322892111

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-'''Unreleased structure'''
+{{STRUCTURE_4ci8|  PDB=4ci8  |  SCENE=  }}
+===Crystal structure of the tandem atypical beta-propeller domain of EML1===
+{{ABSTRACT_PUBMED_24706829}}
-The entry 4ci8 is ON HOLD  until Paper Publication
+==Function==
+[[http://www.uniprot.org/uniprot/EMAL1_HUMAN EMAL1_HUMAN]] May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic (By similarity).
-Authors: Richards, M.W., Bayliss, R.
+==About this Structure==
+[[4ci8]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CI8 OCA].
-Description: Crystal structure of the tandem atypical beta-propeller domain of EML1
+==Reference==
+<ref group="xtra">PMID:024706829</ref><references group="xtra"/><references/>
+[[Category: Bayliss, R.]]
+[[Category: Richards, M W.]]
+[[Category: Beta propeller]]
+[[Category: Eml1]]
+[[Category: Eml4-alk]]
+[[Category: Hsp90 inhibitor]]
+[[Category: Structural protein]]
+[[Category: Tubulin-binding]]