4nh8: Difference between revisions

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-'''Unreleased structure'''
+{{STRUCTURE_4nh8|  PDB=4nh8  |  SCENE=  }}
+===Correlation between chemotype-dependent binding conformations of HSP90 alpha/beta and isoform selectivity===
+{{ABSTRACT_PUBMED_24332488}}
-The entry 4nh8 is ON HOLD
+==Function==
+[[http://www.uniprot.org/uniprot/HS90A_HUMAN HS90A_HUMAN]] Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.<ref>PMID:15937123</ref> <ref>PMID:11274138</ref>
-Authors: Ernst, J.T., Zuccola, H.J.
+==About this Structure==
+[[4nh8]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NH8 OCA].
-Description: Correlation between chemotype-dependent binding conformations of HSP90 alpha/beta and isoform selectivity
+==Reference==
+<ref group="xtra">PMID:024332488</ref><references group="xtra"/><references/>
+[[Category: Ernst, J T.]]
+[[Category: Zuccola, H J.]]
+[[Category: A/b protein]]
+[[Category: Chaperone]]

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