2tct: Difference between revisions

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[[Image:2tct.gif|left|200px]]<br /><applet load="2tct" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2tct.gif|left|200px]]
caption="2tct, resolution 2.1&Aring;" />
 
'''THE COMPLEX FORMED BETWEEN TET REPRESSOR AND TETRACYCLINE-MG2+ REVEALS MECHANISM OF ANTIBIOTIC RESISTANCE'''<br />
{{Structure
|PDB= 2tct |SIZE=350|CAPTION= <scene name='initialview01'>2tct</scene>, resolution 2.1&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene> and <scene name='pdbligand=CTC:7-CHLOROTETRACYCLINE'>CTC</scene>
|ACTIVITY=
|GENE=
}}
 
'''THE COMPLEX FORMED BETWEEN TET REPRESSOR AND TETRACYCLINE-MG2+ REVEALS MECHANISM OF ANTIBIOTIC RESISTANCE'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2TCT is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=MG:'>MG</scene> and <scene name='pdbligand=CTC:'>CTC</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. This structure supersedes the now removed PDB entry 1TCT. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2TCT OCA].  
2TCT is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. This structure supersedes the now removed PDB entry 1TCT. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2TCT OCA].  


==Reference==
==Reference==
The complex formed between Tet repressor and tetracycline-Mg2+ reveals mechanism of antibiotic resistance., Kisker C, Hinrichs W, Tovar K, Hillen W, Saenger W, J Mol Biol. 1995 Mar 24;247(2):260-80. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=7707374 7707374]
The complex formed between Tet repressor and tetracycline-Mg2+ reveals mechanism of antibiotic resistance., Kisker C, Hinrichs W, Tovar K, Hillen W, Saenger W, J Mol Biol. 1995 Mar 24;247(2):260-80. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7707374 7707374]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: transcription regulation]]
[[Category: transcription regulation]]


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