2uuh: Difference between revisions

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[[Image:2uuh.gif|left|200px]]<br /><applet load="2uuh" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2uuh.gif|left|200px]]
caption="2uuh, resolution 2.15&Aring;" />
 
'''CRYSTAL STRUCTURE OF HUMAN LEUKOTRIENE C4 SYNTHASE IN COMPLEX WITH SUBSTRATE GLUTATHIONE'''<br />
{{Structure
|PDB= 2uuh |SIZE=350|CAPTION= <scene name='initialview01'>2uuh</scene>, resolution 2.15&Aring;
|SITE= <scene name='pdbsite=AC1:So4+Binding+Site+For+Chain+A'>AC1</scene>
|LIGAND= <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=LMT:DODECYL-BETA-D-MALTOSIDE'>LMT</scene>, <scene name='pdbligand=GTT:GLUTATHIONE'>GTT</scene>, <scene name='pdbligand=PAM:PALMITOLEIC+ACID'>PAM</scene> and <scene name='pdbligand=PLM:PALMITIC ACID'>PLM</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Leukotriene-C(4)_synthase Leukotriene-C(4) synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.4.1.20 4.4.1.20]
|GENE=
}}
 
'''CRYSTAL STRUCTURE OF HUMAN LEUKOTRIENE C4 SYNTHASE IN COMPLEX WITH SUBSTRATE GLUTATHIONE'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2UUH is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=NI:'>NI</scene>, <scene name='pdbligand=SO4:'>SO4</scene>, <scene name='pdbligand=LMT:'>LMT</scene>, <scene name='pdbligand=GTT:'>GTT</scene>, <scene name='pdbligand=PAM:'>PAM</scene> and <scene name='pdbligand=PLM:'>PLM</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Leukotriene-C(4)_synthase Leukotriene-C(4) synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.4.1.20 4.4.1.20] Known structural/functional Site: <scene name='pdbsite=AC1:So4+Binding+Site+For+Chain+A'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UUH OCA].  
2UUH is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UUH OCA].  


==Reference==
==Reference==
Structural basis for synthesis of inflammatory mediators by human leukotriene C4 synthase., Martinez Molina D, Wetterholm A, Kohl A, McCarthy AA, Niegowski D, Ohlson E, Hammarberg T, Eshaghi S, Haeggstrom JZ, Nordlund P, Nature. 2007 Aug 2;448(7153):613-6. Epub 2007 Jul 15. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17632546 17632546]
Structural basis for synthesis of inflammatory mediators by human leukotriene C4 synthase., Martinez Molina D, Wetterholm A, Kohl A, McCarthy AA, Niegowski D, Ohlson E, Hammarberg T, Eshaghi S, Haeggstrom JZ, Nordlund P, Nature. 2007 Aug 2;448(7153):613-6. Epub 2007 Jul 15. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17632546 17632546]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Leukotriene-C(4) synthase]]
[[Category: Leukotriene-C(4) synthase]]
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[[Category: leukotriene biosynthesis]]
[[Category: leukotriene biosynthesis]]
[[Category: leukotriene signalling]]
[[Category: leukotriene signalling]]
[[Category: ltc4s]]
[[Category: ltc4]]
[[Category: lyase]]
[[Category: lyase]]
[[Category: mapeg]]
[[Category: mapeg]]
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[[Category: trimer]]
[[Category: trimer]]


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