2mio: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

===Solution NMR Structure of SH3 Domain 1 of Rho GTPase-activating Protein 10 from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR9129A===

~~The entry 2mio is ON HOLD~~

==Function==

[[http://www.uniprot.org/uniprot/RHG10_HUMAN RHG10_HUMAN]] GTPase activator for the small GTPases RhoA and Cdc42 by converting them to an inactive GDP-bound state. Essential for PTKB2 regulation of cytoskeletal organization via Rho family GTPases. Inhibits PAK2 proteolytic fragment PAK-2p34 kinase activity and changes its localization from the nucleus to the perinuclear region. Stabilizes PAK-2p34 thereby increasing stimulation of cell death (By similarity).

~~Authors~~: ~~Xu, X~~., Eletsky, A., ~~Pulavarti, S.V.S.R.~~K.~~, Wang~~, H., ~~Janjua~~, H., ~~Xiao,~~ R~~., Everett, J~~.K., Sukumaran, D.T., ~~Montelione~~, ~~G.T~~., ~~Szyperski, T~~., Northeast ~~Structural Genomics Consortium (NESG)~~

==About this Structure==

[[2mio]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MIO OCA].

~~Description~~: ~~Solution NMR Structure of SH3 Domain 1 of Rho GTPase~~-~~activating Protein 10 from Homo sapiens, Northeast~~ Structural ~~Genomics Consortium (NESG) Target HR9129A~~

[[Category: Eletsky, A.]]

[[Category: Everett, J K.]]

[[Category: Janjua, H.]]

[[Category: Montelione, G T.]]

[[Category: NESG, Northeast Structural Genomics Consortium.]]

[[Category: Pulavarti, S V.S R.K.]]

[[Category: Sukumaran, D K.]]

[[Category: Szyperski, T.]]

[[Category: Wang, H.]]

[[Category: Xiao, R.]]

[[Category: Xu, X.]]

[[Category: Nesg]]

[[Category: Northeast structural genomics consortium]]

[[Category: Protein structure initiative]]

[[Category: Psi-biology]]

[[Category: Structural genomic]]

[[Category: Unknown function]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+{{STRUCTURE_2mio|  PDB=2mio  |  SCENE=  }}
+===Solution NMR Structure of SH3 Domain 1 of Rho GTPase-activating Protein 10 from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR9129A===
-The entry 2mio is ON HOLD
+==Function==
+[[http://www.uniprot.org/uniprot/RHG10_HUMAN RHG10_HUMAN]] GTPase activator for the small GTPases RhoA and Cdc42 by converting them to an inactive GDP-bound state. Essential for PTKB2 regulation of cytoskeletal organization via Rho family GTPases. Inhibits PAK2 proteolytic fragment PAK-2p34 kinase activity and changes its localization from the nucleus to the perinuclear region. Stabilizes PAK-2p34 thereby increasing stimulation of cell death (By similarity).
-Authors: Xu, X., Eletsky, A., Pulavarti, S.V.S.R.K., Wang, H., Janjua, H., Xiao, R., Everett, J.K., Sukumaran, D.T., Montelione, G.T., Szyperski, T., Northeast Structural Genomics Consortium (NESG)
+==About this Structure==
+[[2mio]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MIO OCA].
-Description: Solution NMR Structure of SH3 Domain 1 of Rho GTPase-activating Protein 10 from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR9129A
+[[Category: Eletsky, A.]]
+[[Category: Everett, J K.]]
+[[Category: Janjua, H.]]
+[[Category: Montelione, G T.]]
+[[Category: NESG, Northeast Structural Genomics Consortium.]]
+[[Category: Pulavarti, S V.S R.K.]]
+[[Category: Sukumaran, D K.]]
+[[Category: Szyperski, T.]]
+[[Category: Wang, H.]]
+[[Category: Xiao, R.]]
+[[Category: Xu, X.]]
+[[Category: Nesg]]
+[[Category: Northeast structural genomics consortium]]
+[[Category: Protein structure initiative]]
+[[Category: Psi-biology]]
+[[Category: Structural genomic]]
+[[Category: Unknown function]]