Sandbox Reserved 827: Difference between revisions
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Léa Faivre (talk | contribs) |
Léa Faivre (talk | contribs) |
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But TBK1 can undergo another type of post-translationnal modifications : polyubiquitination. Polyubiquitination in a Lys63 manner on | But TBK1 can undergo another type of post-translationnal modifications : polyubiquitination. Polyubiquitination in a Lys63 manner on | ||
<scene name='56/568025/K30/1'> | <scene name='56/568025/K30/1'>Lys30</scene> helps the activation of the kinase. The same type of modification on <scene name='56/568025/K401/1'>Lys401</scene> is responsible for dimerization. Type Lys48 polyubiquitination on Lys670 is done by DTX4 and is responsible for the degradation of the protein. | ||