Sandbox Reserved 827: Difference between revisions

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But TBK1 can undergo another type of  post-translationnal modifications : polyubiquitination. Polyubiquitination in a Lys63 manner on  
But TBK1 can undergo another type of  post-translationnal modifications : polyubiquitination. Polyubiquitination in a Lys63 manner on  
<scene name='56/568025/K30/1'>K30</scene> helps the activation of the kinase. The same type of modification on <scene name='56/568025/K401/1'>Lys401</scene> is responsible for dimerization. Type Lys48 polyubiquitination on Lys670 is done by DTX4 and is responsible for the degradation of the protein.
<scene name='56/568025/K30/1'>Lys30</scene> helps the activation of the kinase. The same type of modification on <scene name='56/568025/K401/1'>Lys401</scene> is responsible for dimerization. Type Lys48 polyubiquitination on Lys670 is done by DTX4 and is responsible for the degradation of the protein.