Sandbox Reserved 813: Difference between revisions
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There are two diffent domains in the Oct-4 sequence : the Pou-specific domain (POUs) located on the N-terminal subunit and the homeodomain located in the C-terminal subunit of the sequence. [[Image:Structure of Oct-4.jpg]] | There are two diffent domains in the Oct-4 sequence : the Pou-specific domain (POUs) located on the N-terminal subunit and the homeodomain located in the C-terminal subunit of the sequence. [[Image:Structure of Oct-4.jpg]] | ||
The first figure on the left shows an aligment between different transcription factors. We can see that there are few conserved sites between each transcription factors. We can also see the organization of the Oct-4 structure : a POUs linked to an POUh thanks to a linker which is actuaaly an alpha helix. | |||
==Pou-specific domain== | ==Pou-specific domain== | ||