Sandbox Reserved 824: Difference between revisions
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Most of the residues involved are localized on <scene name='56/568022/Hsrp54m_rna_bind/1'>helices 5 and 6</scene>, but a few aminoacids of <scene name='56/568022/Hsrp54m_rna_bind/1'>helixes 4 and 7</scene> also play a role. (inserer image) | Most of the residues involved are localized on <scene name='56/568022/Hsrp54m_rna_bind/1'>helices 5 and 6</scene>, but a few aminoacids of <scene name='56/568022/Hsrp54m_rna_bind/1'>helixes 4 and 7</scene> also play a role. (inserer image) | ||
It was also shown that the SRP54M - SRP RNA interaction is highly dependent of the structural integrity of the SRP54M Core. | It was also shown that the SRP54M - SRP RNA interaction is highly dependent of the structural integrity of the <scene name='56/568022/Hsrp54m_core_and_h1/1'>SRP54M Core structure</scene>. | ||
Experiments conducted with shorter versions of the M-domain, lacking some aminoacids of the Core, showed a loss in SRP RNA binding activity. | Experiments conducted with shorter versions of the M-domain, lacking some aminoacids of the Core, showed a loss in SRP RNA binding activity. | ||
