2vf0: Difference between revisions

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[[Image:2vf0.jpg|left|200px]]<br /><applet load="2vf0" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2vf0.jpg|left|200px]]
caption="2vf0, resolution 3.00&Aring;" />
 
'''CRYSTAL STRUCTURE OF THE THYMIDYLATE SYNTHASE K48Q COMPLEXED WITH 5NO2DUMP AND BW1843U89'''<br />
{{Structure
|PDB= 2vf0 |SIZE=350|CAPTION= <scene name='initialview01'>2vf0</scene>, resolution 3.00&Aring;
|SITE= <scene name='pdbsite=AC1:Ndu+Binding+Site+For+Chain+A'>AC1</scene>, <scene name='pdbsite=AC2:F89+Binding+Site+For+Chain+A'>AC2</scene>, <scene name='pdbsite=AC3:Ndu+Binding+Site+For+Chain+B'>AC3</scene>, <scene name='pdbsite=AC4:F89+Binding+Site+For+Chain+B'>AC4</scene> and <scene name='pdbsite=AC5:So4+Binding+Site+For+Chain+B'>AC5</scene>
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=NDU:2'-DEOXY-5-NITROURIDINE+5'-MONOPHOSPHATE'>NDU</scene> and <scene name='pdbligand=F89:S)-2-(5(((1,2-DIHYDRO-3-METHYL-1-OXOBENZO(F)QUINAZOLIN-9-YL)METHYL)AMINO)1-OXO-2-ISOINDOLINYL)GLUTARIC ACID'>F89</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Thymidylate_synthase Thymidylate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.45 2.1.1.45]
|GENE=
}}
 
'''CRYSTAL STRUCTURE OF THE THYMIDYLATE SYNTHASE K48Q COMPLEXED WITH 5NO2DUMP AND BW1843U89'''
 


==About this Structure==
==About this Structure==
2VF0 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=SO4:'>SO4</scene>, <scene name='pdbligand=NDU:'>NDU</scene> and <scene name='pdbligand=F89:'>F89</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Thymidylate_synthase Thymidylate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.45 2.1.1.45] Known structural/functional Sites: <scene name='pdbsite=AC1:Ndu+Binding+Site+For+Chain+A'>AC1</scene>, <scene name='pdbsite=AC2:F89+Binding+Site+For+Chain+A'>AC2</scene>, <scene name='pdbsite=AC3:Ndu+Binding+Site+For+Chain+B'>AC3</scene>, <scene name='pdbsite=AC4:F89+Binding+Site+For+Chain+B'>AC4</scene> and <scene name='pdbsite=AC5:So4+Binding+Site+For+Chain+B'>AC5</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VF0 OCA].  
2VF0 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VF0 OCA].  
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Single protein]]
Line 28: Line 37:
[[Category: translation regulation]]
[[Category: translation regulation]]


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