2vtk: Difference between revisions

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[[Image:2vtk.jpg|left|200px]]<br /><applet load="2vtk" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2vtk.jpg|left|200px]]
caption="2vtk, resolution 2.80&Aring;" />
 
'''THYMIDINE KINASE FROM HERPES SIMPLEX VIRUS TYPE 1 IN COMPLEX WITH ADP AND DEOXYTHYMIDINE'''<br />
{{Structure
|PDB= 2vtk |SIZE=350|CAPTION= <scene name='initialview01'>2vtk</scene>, resolution 2.80&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=ADP:ADENOSINE-5'-DIPHOSPHATE'>ADP</scene> and <scene name='pdbligand=THM:THYMIDINE'>THM</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Thymidine_kinase Thymidine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.21 2.7.1.21]
|GENE=
}}
 
'''THYMIDINE KINASE FROM HERPES SIMPLEX VIRUS TYPE 1 IN COMPLEX WITH ADP AND DEOXYTHYMIDINE'''
 


==Overview==
==Overview==
Line 7: Line 16:


==About this Structure==
==About this Structure==
2VTK is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Human_herpesvirus_4 Human herpesvirus 4] with <scene name='pdbligand=ADP:'>ADP</scene> and <scene name='pdbligand=THM:'>THM</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Thymidine_kinase Thymidine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.21 2.7.1.21] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VTK OCA].  
2VTK is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Human_herpesvirus_4 Human herpesvirus 4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VTK OCA].  


==Reference==
==Reference==
The structures of thymidine kinase from herpes simplex virus type 1 in complex with substrates and a substrate analogue., Wild K, Bohner T, Folkers G, Schulz GE, Protein Sci. 1997 Oct;6(10):2097-106. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9336833 9336833]
The structures of thymidine kinase from herpes simplex virus type 1 in complex with substrates and a substrate analogue., Wild K, Bohner T, Folkers G, Schulz GE, Protein Sci. 1997 Oct;6(10):2097-106. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9336833 9336833]
[[Category: Human herpesvirus 4]]
[[Category: Human herpesvirus 4]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: additional thymidylate kinase activity]]
[[Category: additional thymidylate kinase activity]]
[[Category: key enzyme in thymidine salvage pathway]]
[[Category: key enzyme in thymidine salvage pathway]]
[[Category: target for anti-herpes viral drugs]]
[[Category: target for anti-herpes viral drug]]
[[Category: transferase]]
[[Category: transferase]]


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