Sandbox Reserved 818: Difference between revisions
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==Mechanism of pertussis toxin== | ==Mechanism of pertussis toxin== | ||
Pertussis toxin | Pertussis toxin acts on target cells through its A protomer which contains the '''enzymatically active S1 subunit'''. <br /> | ||
This subunit catalyzes '''ADP-ribosylation''' of the ''α-subunit of trimeric G proteins'', which disturbs functions of the target cells and therefore lead to various biological effects. | This subunit catalyzes '''ADP-ribosylation''' of the ''α-subunit of trimeric G proteins'', which disturbs functions of the target cells and therefore lead to various biological effects. | ||
