Sandbox Reserved 824: Difference between revisions
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The residues responsible for this interaction are localized in <scene name='56/568022/Hsrp54m_rna_bindv3/1'>helices 4, 5, 6 and 7</scene>, but most particularly in helices 5 and 6. | The residues responsible for this interaction are localized in <scene name='56/568022/Hsrp54m_rna_bindv3/1'>helices 4, 5, 6 and 7</scene>, but most particularly in helices 5 and 6. | ||
A large part of the top is therefore positively charged to bind with the negatively charged 7S RNA. | A large part of the top is therefore positively charged to bind with the negatively charged 7S RNA. | ||
[[Image:Proteopedia charge.png|300px|center|thumb| | [[Image:Proteopedia charge.png|300px|center|thumb| The helices 4, 5, 6 and 7 surfaces are colored in blue on the spacefill model of SRP54 in this picture. For more details see figure 7 of reference 1.]] | ||
It was also shown that the SRP54M - SRP RNA interaction is highly dependent of the structural integrity of the <scene name='56/568022/Hsrp54m_core_and_h1/1'>SRP54M Core structure</scene>. | It was also shown that the SRP54M - SRP RNA interaction is highly dependent of the structural integrity of the <scene name='56/568022/Hsrp54m_core_and_h1/1'>SRP54M Core structure</scene>. | ||
