Sandbox Reserved 815: Difference between revisions
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There are 3 types of '''non-polymeric''' entities that can bind this domain:cadmium ion, chloride ion, water. | There are 3 types of '''non-polymeric''' entities that can bind this domain:cadmium ion, chloride ion, water. | ||
This domain 3HAF of the human prion can bind copper (II) ions with high affinity: '''Cd2+''' [http://en.wikipedia.org/wiki/Cadmium cadnium ions] and '''Cl-''' (chloride ion). Moreover, the entire protein can bind a Cu2+ ions on this NH2 tail and this bond can induce '''conformational change''' with a lot of unknown effect. | This domain 3HAF of the human prion can bind <scene name='56/568013/Ligand/1'>Ligand</scene>(copper (II) ions) with high affinity: '''Cd2+''' [http://en.wikipedia.org/wiki/Cadmium cadnium ions] and '''Cl-''' (chloride ion). Moreover, the entire protein can bind a Cu2+ ions on this NH2 tail and this bond can induce '''conformational change''' with a lot of unknown effect. | ||
In fact, the 3haf domain is only one chain with 2 binding sites for residues CD (H40 and D147)and 1 binding domains for CL S132. | In fact, the 3haf domain is only one chain with 2 binding sites for residues CD (H40 and D147)and 1 binding domains for CL S132. | ||
