4jg4: Difference between revisions
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{{STRUCTURE_4jg4| PDB=4jg4 | SCENE= }} | |||
===Ligand concentration regulates the pathways of coupled protein folding and binding=== | |||
{{ABSTRACT_PUBMED_24364358}} | |||
The | ==Function== | ||
[[http://www.uniprot.org/uniprot/G4ENZ9_BACIU G4ENZ9_BACIU]] RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity).[HAMAP-Rule:MF_00227][SAAS:SAAS000100_004_060152] | |||
==About this Structure== | |||
[[4jg4]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JG4 OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:024364358</ref><references group="xtra"/><references/> | |||
[[Category: Ribonuclease P]] | |||
[[Category: Tonthat, N K.]] | |||
[[Category: Endonuclease]] | |||
[[Category: Hydrolase]] | |||
[[Category: Rna-binding]] | |||
Revision as of 06:55, 22 January 2014
Ligand concentration regulates the pathways of coupled protein folding and binding
Template:ABSTRACT PUBMED 24364358
Function
[G4ENZ9_BACIU] RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity).[HAMAP-Rule:MF_00227][SAAS:SAAS000100_004_060152]
About this Structure
4jg4 is a 1 chain structure. Full crystallographic information is available from OCA.
Reference
- Daniels KG, Tonthat NK, McClure DR, Chang YC, Liu X, Schumacher MA, Fierke CA, Schmidler SC, Oas TG. Ligand Concentration Regulates the Pathways of Coupled Protein Folding and Binding. J Am Chem Soc. 2014 Jan 9. PMID:24364358 doi:https://dx.doi.org/10.1021/ja4086726
