4l4s: Difference between revisions

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'''Unreleased structure'''
==Structural Characterisation of the Apo-form of Human Lactate Dehydrogenase M Isozyme==
<StructureSection load='4l4s' size='340' side='right' caption='[[4l4s]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
[[4l4s]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L4S OCA]. <br>
<b>Related:</b> [[4l4r|4l4r]]<br>
<b>Activity:</b> <span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span><br>
== Disease ==
[[http://www.uniprot.org/uniprot/LDHA_HUMAN LDHA_HUMAN]] Defects in LDHA are the cause of glycogen storage disease type 11 (GSD11) [MIM:[http://omim.org/entry/612933 612933]]. A metabolic disorder that results in exertional myoglobinuria, pain, cramps and easy fatigue.<ref>PMID:2334430</ref> 
== Function ==


The entry 4l4s is ON HOLD  until Paper Publication
== References ==
 
<references/>
Authors: Dempster, S., Harper, S., Moses, J.E., Dreveny, I.
__TOC__
 
</StructureSection>
Description: Structural Characterisation of the Apo-form of Human Lactate Dehydrogenase M Isozyme
[[Category: L-lactate dehydrogenase]]
[[Category: Dempster, S.]]
[[Category: Dreveny, I.]]
[[Category: Harper, S.]]
[[Category: Moses, J E.]]
[[Category: Anaerobic respiration]]
[[Category: Glycolysis]]
[[Category: Oxidoreductase]]