4ocl: Difference between revisions
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{{STRUCTURE_4ocl| PDB=4ocl | SCENE= }} | |||
===Crystal Structure of the Rpn8-Rpn11 MPN domain heterodimer, crystal form Ia=== | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/RPN8_YEAST RPN8_YEAST]] Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.<ref>PMID:9584156</ref> [[http://www.uniprot.org/uniprot/RPN11_YEAST RPN11_YEAST]] Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.<ref>PMID:21075847</ref> | |||
==About this Structure== | |||
[[4ocl]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OCL OCA]. | |||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Bracher, A.]] | |||
[[Category: Pathare, G R.]] | |||
[[Category: 26s proteasome]] | |||
[[Category: Hydrolase]] | |||
[[Category: Isopeptidase activity]] | |||
[[Category: Lid]] | |||
[[Category: Protein binding]] | |||
[[Category: Regulatory particle]] | |||
[[Category: Ubiquitin]] | |||
Revision as of 07:52, 29 January 2014
Crystal Structure of the Rpn8-Rpn11 MPN domain heterodimer, crystal form Ia
Function
[RPN8_YEAST] Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.[1] [RPN11_YEAST] Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.[2]
About this Structure
4ocl is a 6 chain structure. Full crystallographic information is available from OCA.
Reference
- ↑ Glickman MH, Rubin DM, Fried VA, Finley D. The regulatory particle of the Saccharomyces cerevisiae proteasome. Mol Cell Biol. 1998 Jun;18(6):3149-62. PMID:9584156
- ↑ Chen L, Romero L, Chuang SM, Tournier V, Joshi KK, Lee JA, Kovvali G, Madura K. Sts1 plays a key role in targeting proteasomes to the nucleus. J Biol Chem. 2011 Jan 28;286(4):3104-18. doi: 10.1074/jbc.M110.135863. Epub 2010 , Nov 12. PMID:21075847 doi:10.1074/jbc.M110.135863
