2z2m: Difference between revisions
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[[Image:2z2m.gif|left|200px]] | [[Image:2z2m.gif|left|200px]] | ||
'''Cefditoren-Acylated Penicillin-Binding Protein 2X (PBP2X) from Streptococcus pneumoniae''' | {{Structure | ||
|PDB= 2z2m |SIZE=350|CAPTION= <scene name='initialview01'>2z2m</scene>, resolution 2.60Å | |||
|SITE= | |||
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> and <scene name='pdbligand=CDS:(2R)-2-[(1R)-1-{[(2Z)-2-(2-AMINO-1,3-THIAZOL-4-YL)-2-(METHOXYIMINO)ACETYL]AMINO}-2-OXOETHYL]-5-[(Z)-2-(4-METHYL-1,3-THIAZOL-5-YL)VINYL]-3,6-DIHYDRO-2H-1,3-THIAZINE-4-CARBOXYLIC ACID'>CDS</scene> | |||
|ACTIVITY= | |||
|GENE= pbpX ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1313 Streptococcus pneumoniae]) | |||
}} | |||
'''Cefditoren-Acylated Penicillin-Binding Protein 2X (PBP2X) from Streptococcus pneumoniae''' | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
2Z2M is a [ | 2Z2M is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae Streptococcus pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z2M OCA]. | ||
==Reference== | ==Reference== | ||
Crystal structure of cefditoren complexed with Streptococcus pneumoniae penicillin-binding protein 2X: structural basis for its high antimicrobial activity., Yamada M, Watanabe T, Miyara T, Baba N, Saito J, Takeuchi Y, Ohsawa F, Antimicrob Agents Chemother. 2007 Nov;51(11):3902-7. Epub 2007 Aug 27. PMID:[http:// | Crystal structure of cefditoren complexed with Streptococcus pneumoniae penicillin-binding protein 2X: structural basis for its high antimicrobial activity., Yamada M, Watanabe T, Miyara T, Baba N, Saito J, Takeuchi Y, Ohsawa F, Antimicrob Agents Chemother. 2007 Nov;51(11):3902-7. Epub 2007 Aug 27. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17724158 17724158] | ||
[[Category: Protein complex]] | [[Category: Protein complex]] | ||
[[Category: Streptococcus pneumoniae]] | [[Category: Streptococcus pneumoniae]] | ||
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[[Category: CDS]] | [[Category: CDS]] | ||
[[Category: SO4]] | [[Category: SO4]] | ||
[[Category: | [[Category: antibiotic]] | ||
[[Category: biosynthetic protein]] | [[Category: biosynthetic protein]] | ||
[[Category: cefditoren]] | [[Category: cefditoren]] | ||
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[[Category: peptidoglycan synthesis]] | [[Category: peptidoglycan synthesis]] | ||
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