Introduction to protein structure: Difference between revisions

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== Levels of Protein Structure ==
== Levels of Protein Structure ==
<StructureSection load='1A3N' size='350' side='right' caption='Structure of Hemoglobin (PDB entry [[1A3N]])' scene=''>
<StructureSection load='1A3N' size='350' side='right' caption='Structure of Hemoglobin (PDB entry [[1A3N]])' scene=''>
Proteins are condensation polymers of amino acids.  The <scene name='57/575866/Primary_sequence/1'>primary structure</scene> is the amino acid sequence.  The <scene name='57/575866/Secondary_sequence/1'>secondary structure</scene> is the local structure over short distances.  This level of structure is stabilized by <scene name='57/575866/Alpha_helix_h_bond/2'>hydrogen bonds</scene> between the backbone amide groups.
Proteins are condensation polymers of amino acids.  The <scene name='57/575866/Primary_sequence/1'>primary structure</scene> is the amino acid sequence.  The <scene name='57/575866/Secondary_sequence/1'>secondary structure</scene> is the local structure over short distances.  This level of structure is stabilized by <scene name='57/575866/H_bond_a_helix/1'>hydrogen bonds</scene> along the <scene name='57/575866/Backbone/1'>backbone</scene>.  These secondary structures pack together to form the overall form of the entire peptide chain, called the <scene name='57/575866/Tertiary/1'>tertiary structure</scene>.  Some proteins, such as the displayed hemoglobin molecule, have more than one polypeptide chain that associate to form the functional unit of the protein; this is called <scene name='57/575866/Tertiary/2'>quaternary structure</scene>.
 
'''Questions based upon these scenes:'''
What is the primary sequence shown in the first link?
Is the secondary structure shown an alpha helix or beta sheet?
The ith C=O of the backbone is hydrogen bonded to which N(-H) (use i +/- # to represent the number)?
What atom does this program NOT show?


== Ways of representing protein structure ==
== Ways of representing protein structure ==